3-Methoxybenzonitrile CAS 1527-89-5 Active Pharmaceutical
|Synonym||m-Anisonitrile; AKOS B004087; 3-ANISONITRILE;
3-METHOXYBENZONITRILE; 3-CYANOANISOLE; M-METHOXYBENZONITRILE;
Benzonitrile, 3-methoxy-; Benzonitrile, m-methoxy-|
|Density||1.089 g/mL at 25 °C|
3-Methoxybenzonitrile, also known as 3-methoxy benzonitrile,
m-methoxy benzonitrile, colorless or slightly yellow liquid.
|Water||Quality standard||meets company specification|
Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Not available.
Incompatibilities with Other Materials: Strong oxidizing agents.
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide,
carbon dioxide, nitrogen.
Used as a pharmaceutical intermediate, it is an important
intermediate of the new antipyretic analgesic - tapentadol. The
drug is mainly used to relieve moderate and severe acute pain,
especially for the relief of adults over 18 years of age. Its quick
release tablets were approved by the US Food and Drug
Administration (trade name: NUCNTA) in November 2008 to relieve
moderate and severe acute pain;Its sustained-release tablets were
approved for marketing in August 2012 (trade name: NUCYNTA ER) for
the treatment of adult diabetic neuropathy (DPN) -related
neuropathic pain.In addition, it also can participate in a variety
of organic synthesis.
Store in a cool, dry place, avoid direct sunlight. Store in a
tightly closed container.
200kgs/iron drum with plastic lining
Exposure Controls, Personal Protection
Engineering Controls: Use adequate general or local exhaust
ventilation to keep airborne concentrations below the permissible
Personal Protective Equipment
Eyes: Wear safety glasses and chemical goggles if splashing is
Skin: Wear appropriate protective gloves and clothing to prevent
Clothing: Not available.
Harmful by inhalation, in contact with skin and if swallowed.
Potential Health Effects
The toxicological properties of this material have not been
investigated. Use appropriate procedures to prevent opportunities
for direct contact with the skin or eyes and to prevent inhalation.
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CAS 1527-89-5 in China. We can provide costomers with
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